Impact of pharmaceuticals on human health through water

Dear professionals, my colleague attended a meeting which dealt with the "Priority Substances in the Field of Water". Background of the meeting was the change of appendix X of the Water Framework Directive which deals with those substances. One of the discussions circulated around the impact of pharmaceuticals (or to be precise residues of pharmaceuticals) in water resources. The representative of the pharma industry argued that there is no scientific evidence of negative impacts of those substances on human health (yet). I would like to know if you guys know anything about it? Is there any report published about this? I doubt that there are no impacts and if there are no direct health impacts I can imagine that there might be negative impacts on the environment . Answers/links/advices where to look up/... are highly appreciated in preparation for the next meetings. Thanks in advance, Melina Tenbrock